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Allele : Kcna1<tm1Jmay> potassium voltage-gated channel, shaker-related subfamily, member 1; targeted mutation 1, James Maylie

Primary Identifier  MGI:2655686 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Kcna1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A valine to alanine missense mutation in codon 408 (V408A, equivalent to that found in episodic ataxia type-1 (EA1) patients) was introduced via homologous recombination. A floxed neo cassette inserted in the 3' untranslated region was removed in vivo by cre mediated excision.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Kcna1<V408A>,
  • Kcna1<V408A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories