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Allele : Ifnb1<tm1Tl> interferon beta 1, fibroblast; targeted mutation 1, Tomas Leanderson

Primary Identifier  MGI:2657141 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ifnb1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by insertion of a neo-derived cassette into the region encoding the first 4 amino acids. The targeting construct includes a mouse immunoglobulin lambda 2 reporter sequence. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of mouse embryonic fibroblasts.
  • mutations:
  • Insertion
  • synonyms:
  • IFN-beta<0>,
  • IFN-beta-,
  • IFN-beta-,
  • IFN-beta<0>,
  • Ifnb<tm1(Lambda2 (315))GBF>,
  • Ifnb<tm1(Lambda2 (315))GBF>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

35 Publication categories

Trail: Allele