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Allele : Gab2<tm1Thir> growth factor receptor bound protein 2-associated protein 2; targeted mutation 1, Toshio Hirano

Primary Identifier  MGI:2660754 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gab2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The exon encoding a major portion of the pleckstrin homology (PH) domain (amino acids 28-128) was replaced with a neomycin resistance gene via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by Western blot analysis of testis proteins.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Gab2<->,
  • Gab2<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

19 Publication categories