| Primary Identifier | MGI:2662436 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Sh2b1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A genomic fragment extending from within exon 2 through exon 8 was replaced with a PGK-neo cassette inserted by homologous recombination. The deleted region encoded the PH and SH2 domains of the protein. Transcript was undetected in the cerebellums of homozygous mutant mice by Northern blot analysis. |