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Allele : Sh2b1<tm1Ayos> SH2B adaptor protein 1; targeted mutation 1, Akihiko Yoshimura

Primary Identifier  MGI:2662436 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sh2b1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment extending from within exon 2 through exon 8 was replaced with a PGK-neo cassette inserted by homologous recombination. The deleted region encoded the PH and SH2 domains of the protein. Transcript was undetected in the cerebellums of homozygous mutant mice by Northern blot analysis.
  • mutations:
  • Disruption caused by insertion of vector
  • synonyms:
  • Sh2B<->,
  • Sh2B<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories