| Primary Identifier | MGI:2667230 | Allele Type | Chemically induced (ENU) |
| Gene | Nfkb2 | Inheritance Mode | Recessive |
| Strain of Origin | C57BL/6JSfdAnu | Is Recombinase | false |
| Is Wild Type | false | Project Collection | APF ENU Mutagenesis |
| molecularNote | A T-to-A point mutation at nucleotide 3193 disrupted the exon 7 splice acceptor site within intron 6. Normal protein was undetected by Western blot analysis of homozygous mutant mice. The mutation resulted in an accumulation of unspliced intermediates as well as mutant transcripts that involved aberrant splicing of exon 6 to sites within exon 7 and premature stop codons. |
