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Allele : Foxo3<tm1Rdp> forkhead box O3; targeted mutation 1, Ronald DePinho

Primary Identifier  MGI:2668317 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Foxo3
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
description 

Phenotypic Similarity to Human Syndrome: Granulosa Cell Tumor of the ovary J:232961.

molecularNote  Exon 2, which is the first coding exon, was flanked by a loxP-frt-neo-frt cassette in intron 1 and single loxP site in intron 2. Mice carrying this allele were bred with cre transgenic mice to generate Foxo3tm1.1Rdp.
  • mutations:
  • Insertion
  • synonyms:
  • Foxo3<f>,
  • FoxO3<L>,
  • FoxO3<L>,
  • Foxo3<f>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

102 Publication categories