| Primary Identifier | MGI:2667379 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Trpv4 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance gene was inserted into exon 4 which encodes the ankyrin-repeat domain. Transcripts were undetectable by RT-PCR and Northern blot in trigeminal root and dorsal root ganglia of homozygous animals. Immunohistochemical staining of the dorsal root ganglion confirmed the success of gene disruption. |
