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Allele : Trpv4<tm1Msz> transient receptor potential cation channel, subfamily V, member 4; targeted mutation 1, Makoto Suzuki
Primary Identifier  MGI:2667379 Allele Type  Targeted
Attribute String  Null/knockout Gene  Trpv4
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene was inserted into exon 4 which encodes the ankyrin-repeat domain. Transcripts were undetectable by RT-PCR and Northern blot in trigeminal root and dorsal root ganglia of homozygous animals. Immunohistochemical staining of the dorsal root ganglion confirmed the success of gene disruption.
  • mutations:
  • Insertion
  • synonyms:
  • TRPV4KO,
  • Trpv4<->,
  • Trpv4<->,
  • TRPV4KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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