| Help | About | Contact Us

Allele : Pglyrp1<tm1Rdz> peptidoglycan recognition protein 1; targeted mutation 1, Roman Dziarski

Primary Identifier	MGI:2670590	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Pglyrp1
Transmission	Germline	Strain of Origin	129S5/SvEvBrd
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 1 was replaced with a cassette containing IRES-lacZ and neo. Transcript and protein were undetected in homozygous mutant mice by RT-PCR and Western blot analyses of bone marrow.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
PGRP-S<->,
PGRP-S<->

earliestPublication:
Dziarski R, et al. (2003) Defect in neutrophil killing and increased susceptibility to infection with nonpathogenic gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)-deficient mice. Blood 102(2):689-97

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

15 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=74440215

MouseMine