| Primary Identifier | MGI:2671068 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Tkt |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Genomic sequences including intron 2 and exon 3 were replaced with a neomycin selection cassette. Western blot analysis demonstrated that various tissues of heterozygous mice expressed half the amount of encoded protein, and enzymatic assays demonstrated reductions in enzyme activity in various tissues of heterozygous mice. |
