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Allele : Pctp<tm1Bor> phosphatidylcholine transfer protein; targeted mutation 1, Piet Borst

Primary Identifier	MGI:2673156	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Pctp
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A neomycin selection gene replaced exons C and D by homologous recombination. Western blot analysis demonstrated that no detectable protein product was made in the cytosol of cells derived from homozygous mice.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Pctp<->,
Pctp<->,
Pc-tp -,
Pc-tp -

earliestPublication:
van Helvoort A, et al. (1999) Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces. Proc Natl Acad Sci U S A 96(20):11501-6

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

16 Publication categories

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