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Allele : Rttn<Gt(pGT1.8geo)7Pgr> rotatin; gene trap 7, Peter Gruss

Primary Identifier  MGI:2674124 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Rttn
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
description 

Authors note a phenotypic similarity of this mutation to No turning (nt).

molecularNote  An integration of the gene trap vector occurred such that the splice donor at position 1101 to 1102 of the cDNA becomes fused to the splice acceptor in the vector DNA. A protein consisting of the first 281 amino acids of the Rttn gene fused to the beta-galactosidase/neomycin gene is expressed from this allele.
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • XV-53,
  • rotatin<GT>,
  • XV-53,
  • rotatin<GT>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories