Primary Identifier | MGI:2674124 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Rttn |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
description | Authors note a phenotypic similarity of this mutation to No turning (nt). |
molecularNote | An integration of the gene trap vector occurred such that the splice donor at position 1101 to 1102 of the cDNA becomes fused to the splice acceptor in the vector DNA. A protein consisting of the first 281 amino acids of the Rttn gene fused to the beta-galactosidase/neomycin gene is expressed from this allele. |