| Primary Identifier | MGI:2673557 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Icosl |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Sequence encompassing a portion of the promoter and exons encoding the initiator methionine, signal peptide, and IgV-like domain were replaced with a neomycin resistance gene inserted by homologous recombination. Neither full length nor truncated transcript was detected by Northern blot or RT-PCR analyses of message isolated from homozygous mutant spleen tissue. |