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Allele : Fabp3<tm1Bin> fatty acid binding protein 3, muscle and heart; targeted mutation 1, Bert Binas

Primary Identifier  MGI:2677970 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fabp3
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
description  Homozygous mice may provide a model for some human cardiomyopathies thought to be caused by depressed myocardial long chain fatty acid utilization (J:54614).
molecularNote  A sequence fragment containing the entire coding region was replaced with an PGK-HRPT mini gene inserted by homologous recombination. Neither transcript nor protein was detected through Northern and Western blot analysis of homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • H-FABP<->,
  • H-FABP<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

22 Publication categories