Primary Identifier | MGI:2678361 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Gucy2c |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 1 was replaced with an hprt cassette inserted by homologous recombination. Transcript was undetected in the jejunum and ileum of homozygous mutant mice by Northern blot analysis. Western blot analysis using an antibody against the extracellular domain indicated the absence of protein in the jejunum. |