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Allele : Pmaip1<tm1Ast> phorbol-12-myristate-13-acetate-induced protein 1; targeted mutation 1, Andreas Strasser

Primary Identifier  MGI:2681649 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pmaip1
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 and 3 which contain the two BH3 interaction domains were replaced with a floxed PGK-hygromycin resistance cassette. The resistance gene was excised in vivo by crossing to C57BL/6 Deleter mice. Gene disruption was confirmed by RT-PCR and by Northern blot analysis.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • noxa<->,
  • noxa<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

42 Publication categories