| Primary Identifier | MGI:2683493 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Icosl |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Two loxP sites were inserted so as to flank the two exons encoding the extracellular Ig-like domains as well as an FRT enclosed neomycin resistance gene (Icosltm2Cdon. These two exons and the neomycin gene were subsequently removed by crossing F1 mice with a cytomegalovirus-cre transgenic mouse. Absence of protein product was confirmed immunologically. |