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Allele : Icosl<tm1Cdon> icos ligand; targeted mutation 1, Chen Dong

Primary Identifier  MGI:2683493 Allele Type  Targeted
Attribute String  Null/knockout Gene  Icosl
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Two loxP sites were inserted so as to flank the two exons encoding the extracellular Ig-like domains as well as an FRT enclosed neomycin resistance gene (Icosltm2Cdon. These two exons and the neomycin gene were subsequently removed by crossing F1 mice with a cytomegalovirus-cre transgenic mouse. Absence of protein product was confirmed immunologically.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • B7h<->,
  • B7h<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele