Primary Identifier | MGI:2687365 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd79a |
Transmission | Germline | Strain of Origin | BALB/cJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 2 and 3 were replaced by a loxP site, an EGFP gene, a cDNA cassette containing exons 2 - 5 in inverse orientation and a floxed neomycin resistance gene. Lack of mRNA expression was demonstrated by Northern blot analysis. Although designed to be a cre dependent conditional allele capable of expressing either EGFP or Ig-alpha, neither of the inserted genes were ever expressed. |