Primary Identifier | MGI:2684302 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | F13a1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 2.5 kb fragment encompassing exon 7 was replaced with a neomycin selection cassette inserted by homologous recombination. Both coagulation factor XIII enzymatic activity and fibrin gamma-dimerization were undetected in plasma from homozygous mutant mice. |