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Allele : Ptpro<tm1Wig> protein tyrosine phosphatase receptor type O; targeted mutation 1, Roger C Wiggins

Primary Identifier  MGI:2687220 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptpro
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 3' portion of exon 2 was replaced with a neomycin selection cassette inserted by homologous recombination. Normal protein was undetected by Western blot and immunofluorescence analyses of homozygous mutant mice, however a polypeptide larger than that produced by the endogenous locus was detected at levels less than 1.2% those of wild-type.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • GLEPP1 knockout,
  • Ptpro<->,
  • Ptpro<->,
  • GLEPP1 knockout
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

12 Publication categories