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Allele : Itgam<tm1Rws> integrin alpha M; targeted mutation 1, Richard W Stokes

Primary Identifier  MGI:3027319 Allele Type  Targeted
Attribute String  Null/knockout Gene  Itgam
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  3' and 5' portions of exons 13 and 14, respectively, were replaced with a neomycin selection cassette inserted by homologous recombination. The insertion was expected to preclude the translation of the C-terminal, which includes the majority of the metal-binding domain and the transmembrane domain.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • CD11b-,
  • CD11b-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories