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Allele : Pgr<tm1Lyd> progesterone receptor; targeted mutation 1, John P Lydon

Primary Identifier  MGI:3032652 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Pgr
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A lacZ gene was inserted in frame within exon 1 followed by a PGK-neomycin resistance gene. This replaced sequence from 356bp to 724bp downsteam of the initiator codon for the "B" isoform. As a result, the coding sequence for a 122aa fragment was removed including the initiation codon for the "A" isoform. Care was taken not to disrupt the estrogen response elements.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • PR<lacZ>,
  • PRKO<lacZ>,
  • PR<lacZ>,
  • PRKO<lacZ>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

17 Publication categories