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Allele : Prm2<tm1Eddy> protamine 2; targeted mutation 1, Edward M Eddy

Primary Identifier  MGI:3039800 Allele Type  Targeted
Attribute String  Null/knockout Gene  Prm2
Transmission  Chimeric Strain of Origin  129
Is Recombinase  false Is Wild Type  false
description  ES cell line was either R1 or BK4. Haploinsufficiency of Prm2 prevents genetic transmission of the mutated allele and generation of non-chimeric heterozygous mice. All phenotype data reported are from chimeric mice.
molecularNote  A neo cassette replaced 66 bp in exon 1 via homologous recombination. Analysis of 129 derived sperm from chimeras showed reduced PRM1 and PRM2 protein expression.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories