Primary Identifier | MGI:3043150 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Robo3 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A portion of exon 1 including the ATG start site was replaced with a cassette containing an IRES element, a tau-GFP fusion gene, a loxP site, a PGK-1 promoter, a neomycin resitance gene, a PGK-1 polyA tail and a second loxP site. Western blot analysis confirmed the absence of protein in spinal cords from homozygous null mice. The tau-GFP fusion protein is expressed from the Robo3 promoter. |