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Allele : Ptpn22<tm1Achn> protein tyrosine phosphatase, non-receptor type 22 (lymphoid); targeted mutation 1, Andrew C Chan

Primary Identifier	MGI:3043469	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Ptpn22
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 8, encoding the phosphatase domain, was replaced with a neo cassette via homologous recombination. Immunoblot analysis confirmed the absence of wild-type or truncated protein in thymocytes and splenocytes from homozygotes.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
pep(E8)-,
pep-,
pep(E8)-,
pep-

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

12 Publication categories

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