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Allele : Ptpn22<tm2Achn> protein tyrosine phosphatase, non-receptor type 22 (lymphoid); targeted mutation 2, Andrew C Chan
Primary Identifier  MGI:3043477 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptpn22
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The translation initiation methionine in exon 1 was mutated from ATGG to CTGC and a puromycin resistance cassette added via homologous recombination. Immunoblot analysis confirmed the absence of wild type or truncated protein in thymocytes and splenocytes from homozygotes.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • pep(E1)-,
  • pep(E1)-,
  • pep-,
  • pep-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

17 Publication categories





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