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Allele : Epha5<tm1Jgf> Eph receptor A5; targeted mutation 1, John G Flanagan

Primary Identifier  MGI:3043641 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Epha5
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The endogenous gene was disrupted by the insertion of a cassette containing lacZ and PGK-neo. Beta galactosidase activity was detected in mutant mice indicating the production of a fusion protein predicted to consist of the extracellular, transmembrane, and juxtamembrane domains followed by beta-galactosidase. The protein putatively lacks the entire tyrosine kinase and C-terminal domains, but the kinase-independent functions are expetcted to remain intact.
  • mutations:
  • Insertion
  • synonyms:
  • Epha5<lacZ>,
  • Epha5<lacZ>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories