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Allele : Spi1<tm1Kast> Spi-1 proto-oncogene; targeted mutation 1, Philippe Kastner

Primary Identifier  MGI:3044765 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Spi1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A 22 bp segment of exon 1 was replaced with a rabbit beta globin intron, an enhanced GFP sequence and an SV40 polyadenylation signal via homologous recombination. Both mRNA and protein were undetectable in fetal liver from homozygous mice. GFP expression correlated well with endogenous Sfpi1 expression.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • PU.1<G>,
  • PU.1<G>,
  • PU-1-GFP,
  • PU-1-GFP
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

13 Publication categories