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Allele : H2-T23<tm1Cant> histocompatibility 2, T region locus 23; targeted mutation 1, Harvey Cantor

Primary Identifier  MGI:3044027 Allele Type  Targeted
Attribute String  Null/knockout Gene  H2-T23
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1 - 3 were replaced with a neo cassette via homologous recombination. This insertion introduced a frameshift. The absence of protein expression in activated thymocytes and splenic T cells was confirmed by flow cytometry.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Qa-1b<->,
  • Qa-1<->,
  • Qa-1<->,
  • Qa-1 KO,
  • Qa-1 KO,
  • Qa-1b<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

28 Publication categories