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Allele : Twist2<tm1(cre)Dor> twist basic helix-loop-helix transcription factor 2; targeted mutation 1, David M Ornitz
Primary Identifier  MGI:3044412 Allele Type  Targeted
Attribute String  Recombinase Gene  Twist2
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  true Is Wild Type  false
molecularNote  Exon 1 was replaced with a cre recombinase gene and an FRT-flanked neo cassette. Southern blot analysis confirmed recombination. Cre was expressed in the developing skeleton, specifically in mesenchymal condensations giving rise to both osteoblast and chondrocyte lineages.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Dermo1Cre,
  • DM1-Cre,
  • twist-2<->,
  • Dermo1<cre>,
  • twist-2<->,
  • Dermo1Cre,
  • Twist2<tm1(cre)Eno>,
  • Dermo1<cre>,
  • Dermo-1<Cre>,
  • Dermo-1<Cre>,
  • Twist2<tm1(cre)Eno>,
  • Dermo<cre>,
  • DM1-Cre,
  • Dermo1-Cre,
  • Dermo<cre>,
  • Dermo1-Cre
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

88 Publication categories





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