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Allele : Rr27<tm2Rohl> regulatory region 27; targeted mutation 2, Rolf Ohlsson
Primary Identifier  MGI:3045724 Allele Type  Targeted
Attribute String  Modified regulatory region Gene  Rr27
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  CTCF target site 4 within the imprinting control region (ICR) was modified from a central GTGG motif to ATAT via homologous recombination. A floxed neomycin resistance gene cassette that was included in the targeting vector was excised via in vivo cre-mediated recombination in the germ line. Southern blot analysis and sequence analysis confirmed recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • H19<tm2Rohl>,
  • H19<tm2Rohl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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