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Allele : Xist<tm2Nbd> inactive X specific transcripts; targeted mutation 2, Neil Brockdorff

Primary Identifier  MGI:3047784 Allele Type  Targeted
Gene  Xist Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  A sequence between 1 and 9 kb upstream of the P1 start site was deleted and replaced with a floxed PGK-neomycin resistance gene. Southern blot and PCR confirmed recombination. RT-PCR of mutants indicated antisense expression was not affected and ectopic sense transcription was detected upstream of Xist, as well as elevated transcription within the Xist locus.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Delta5'+neo,
  • Delta5'+neo
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories