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Allele : Rps12-ps1/Xist<tm1.1Nbd> inactive X specific transcripts; targeted mutation 1, Neil Brockdorff

Primary Identifier  MGI:3047793 Allele Type  Targeted
Attribute String  Null/knockout Gene  Xist
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Transient cre expression excised the floxed neo in Rps12-ps1/Xisttm1Nbd, which had a 2.5 kb sequence deletion between 5.5 and 8 kb upstream of Xist, including Rps12-ps1 and spanning a site thought to include an upstream promoter for Xist. RT-PCR showed presence of antisense transcription upstream of Xist in mutants where none is present in wild-type.
  • mutations:
  • Intergenic deletion
  • synonyms:
  • DeltaCJdeltaneo,
  • DeltaCJdeltaneo
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories