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Allele : St8sia2<tm1Jxm> ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; targeted mutation 1, Jamey Marth

Primary Identifier  MGI:3051219 Allele Type  Targeted
Attribute String  Null/knockout Gene  St8sia2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 4, encoding a significant portion of the sailyl motif L, was deleted upon Cre mediated deletion of the floxed region including the exon and a tk-neo cassette. Southern blot confirmed recombination and RT-PCR indicated that the truncated form of mRNA was produced in heterozygous and homozygous mutants. The mutant cDNA was found to be inactive.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • St8sia-II-,
  • St8sia-II-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

33 Publication categories