| Primary Identifier | MGI:3051882 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Cckar |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A PGK-neo replaced exon 3, which encodes a portion of the third transmembrane domain and the second intracellular loop including the "ERY" motif. Southern blot of mutant mice indicated successful recombination. Testing for 125I-CCK-8 binding in pancreatic membranes mutant mice indicated showed no displaceable binding and therefore a lack a Cckar receptors. |
