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Allele : Cdk6<tm1Bbd> cyclin dependent kinase 6; targeted mutation 1, Mariano Barbacid
Primary Identifier  MGI:3053975 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cdk6
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-neo cassette replaced the first coding exon, which contains the ATG as well as the PLSTIRE domain essential for cyclin binding. PCR confirmed recombination in mutant mice. Immunohistochemical analysis of lymphocytes indicated lack of protein expression in mutants.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Cdk6<->,
  • Cdk6<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

22 Publication categories





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