| Primary Identifier | MGI:3056440 | Allele Type | Targeted |
| Gene | Isl2 | Transmission | Germline |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The coding sequence for Epha3 and a floxed neo cassette was inserted into the endogenous locus and placed under the regulatory elements of Isl2. The construct encoded a bicistronic mRNA as shown by in situ hybridization of neonates, showing a mosaic pattern of EphA3 expression that was similar to the pattern of endogenous Isl2 expression. Isl2 expression was not perturbed. |
