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Allele : Cd83<lcd4> CD83 antigen; low CD4 cell

Primary Identifier	MGI:3055293	Allele Type	Chemically induced (ENU)
Gene	Cd83	Inheritance Mode	Not Specified
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

The last exon contains a missense mutation that changes the stop codon to an arginine, extending the protein by 55 amino acids. Immunohistochemistry was unable to detect protein expression and Western blot revealed a severe reduction in the amount of protein.

mutations:
Nucleotide substitutions

synonyms:
LCD4.1,
CD83mu,
LCD4.1,
CD83mu

earliestPublication:
Garcia-Martinez LF, et al. (2004) A novel mutation in CD83 results in the development of a unique population of CD4+ T cells. J Immunol 173(5):2995-3001

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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