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Allele : Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy transgene insertion, Winston C Y Yu

Primary Identifier	MGI:3510918	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy
Strain of Origin	ICR	Is Recombinase	false
Is Wild Type	false

molecularNote

This transgene consists of the mouse Rnu6 promoter, a loxP site, a CMV promoter, EGFP, and an Abca1 siRNA. Without cre mediated recombination only EGFP is expressed. After cre mediated recombination the Abca1 siRNA is expressed. Six founders were generated.

mutations:
Insertion

synonyms:
SIRIUS-ABCA1,
SIRIUS-ABCA1

earliestPublication:
Chang HS, et al. (2004) Using siRNA technique to generate transgenic animals with spatiotemporal and conditional gene knockdown. Am J Pathol 165(5):1535-41

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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