Primary Identifier | MGI:3511494 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Traf2 |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 3 was flanked by loxP sites followed by a floxed neo cassette. The neo cassette was removed in ES cells by transient transfection with a vector driving expression of Cre recombinase, leaving exon 3 flanked by loxP sites. Western blot analysis of lymph node B cells showed that expression levels did not differ from that of wild-type. |