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Allele : Grin2c<tm1(Grin2b)Ulme> glutamate receptor, ionotropic, NMDA2C (epsilon 3); targeted mutation 1, Ulrich, LM Eisel

Primary Identifier  MGI:3513208 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Null/knockout Gene  Grin2c
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A cDNA encoding Grin2b and a neomycin resistance gene was inserted directly 3' of the ATG and thereby replaced the endogenous signal sequence. In situ hybridization of brain sections indicated that Grin2b transcript was present in mutant mice. Western blot also indicated the lack of Grin2c protein, while Grin2b protein was present.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • NR2C-2B,
  • NR2C-2B
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories