|  Help  |  About  |  Contact Us

Allele : Top2b<tm2Jcw> topoisomerase (DNA) II beta; targeted mutation 2, James C Wang

Primary Identifier  MGI:3521850 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Top2b
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A self excising neomycin resistance cassette together with an upstream loxP site was inserted in one intron (4?) and a second loxP site was inserted in the third downstream exon. The presence or absence of the neomycin cassette was assessed by PCR but did not affect selection of mice for breeding since the resistance cassette was contained between the two loxP sites.
  • mutations:
  • Insertion
  • synonyms:
  • top2beta<flox2>,
  • top2beta<flox2>,
  • top2beta<flox1>,
  • top2beta<flox1>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

11 Publication categories