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Allele : Ntrk3<tm1(cre)Lfr> neurotrophic tyrosine kinase, receptor, type 3; targeted mutation 1, Louis F Reichardt

Primary Identifier  MGI:3521571 Allele Type  Targeted
Attribute String  Recombinase Gene  Ntrk3
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  true Is Wild Type  false
molecularNote  An IRES-Cre-SV40pA and FRT-flanked neo cassette was inserted 52 bp downstream of the stop codon into exon 18. Crossing with mice expressing Flp recombinase removed the neo. Northern blot showed expression of a shorter transcript than wild-type, indicating that the wild-type transcript contains a long 3' UTR, which was truncated by the insertion of the SV40 after the Cre.
  • mutations:
  • Insertion
  • synonyms:
  • Ntrk3<tm(cre)>1Lfr,
  • Ntrk3<tm(cre)>1Lfr,
  • Ntrk3<tm1(cre)Rice>,
  • Ntrk3<tm1(cre)Rice>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

12 Publication categories