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Allele : Adam8<tm1Bbl> a disintegrin and metallopeptidase domain 8; targeted mutation 1, Carl P Blobel
Primary Identifier  MGI:3527133 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Adam8
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An IRES-Beta-galactosidase and neo cassette replaced the catalytic and disintegrin domains. Western blot analysis of lungs confirmed that Adam8 protein was abolished in mutant animals. X-gal staining showed that the endogenous promoter drove lacZ expression in lung tissue.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Adam8<->,
  • Adam8<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

19 Publication categories





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