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Allele : Smc1b<tm1Jess> structural maintenance of chromosomes 1B; targeted mutation 1, Rolf Jessberger

Primary Identifier  MGI:3573932 Allele Type  Targeted
Attribute String  Null/knockout Gene  Smc1b
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 10, which codes for 40% of the hinge domain, essential to the formation of Smc heterodimers, was targeted for replacement by a tk-neo cassette. Immunoblotting of testis nuclear extracts confirmed the absence of wild-type protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Smc1Beta<->,
  • Smc1Beta<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

22 Publication categories