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Allele : Gnrhr<hh> gonadotropin releasing hormone receptor; hypogonadotrophic hypogonadism

Primary Identifier  MGI:3574585 Allele Type  Chemically induced (ENU)
Gene  Gnrhr Inheritance Mode  Recessive
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  This allele has a T to C transition in exon 1, 350 bp downstream of the start codon, causing a leucine to proline substitution at position 117, at the N-terminal junction of the third transmembrane domain. Real-time RT-PCR indicated that mRNA levels are 8-fold higher in homozygous mutants.
  • mutations:
  • Single point mutation
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories