Primary Identifier | MGI:3574585 | Allele Type | Chemically induced (ENU) |
Gene | Gnrhr | Inheritance Mode | Recessive |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This allele has a T to C transition in exon 1, 350 bp downstream of the start codon, causing a leucine to proline substitution at position 117, at the N-terminal junction of the third transmembrane domain. Real-time RT-PCR indicated that mRNA levels are 8-fold higher in homozygous mutants. |