| Primary Identifier | MGI:3575405 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Smpd3 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 1 was interrupted by the insertion of a PGK-neo cassette. Exon 1 encodes the two putative transmembrane domains and part of the catalytic site of the protein. Northern blot of brains from mutants demonstrated the lack of wild-type transcript. Western blot of brain protein extract from mutants confirms absence of protein. |
