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Allele : Ptgs1<tm1Fun> prostaglandin-endoperoxide synthase 1; targeted mutation 1, Colin D Funk

Primary Identifier  MGI:3576237 Allele Type  Targeted
Attribute String  Hypomorph Gene  Ptgs1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed PGK-neo was inserted into intron 10 to create this hypomorphic allele. Western blot showed that protein was dramatically reduced in mutant macrophages to approximately 10% of wild-type levels.
  • mutations:
  • Insertion
  • synonyms:
  • PGHS1<Neo>,
  • PGHS1<Neo>,
  • COX-1 KD,
  • COX-1 KD
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

12 Publication categories