Primary Identifier | MGI:3578093 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Dicer1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
description | Phenotypic Similarity to Human Syndrome: myelodysplastic syndrome (Dicer1tm1Mmk/Dicer1tm1Mmk Tg(Sp7-tTA,tetO-EGFP/cre)1Amc; J:158901) |
molecularNote | Exons 20 and 21, which contain the RNaseII domain, were flanked with loxP sites. A neo with a 5' loxP site was included in the targeting vector and was inserted into intron 19. |