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Allele : Dicer1<tm1Mmk> dicer 1, ribonuclease type III; targeted mutation 1, Matthias Merkenschlager

Primary Identifier  MGI:3578093 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Dicer1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: myelodysplastic syndrome (Dicer1tm1Mmk/Dicer1tm1Mmk Tg(Sp7-tTA,tetO-EGFP/cre)1Amc; J:158901)
molecularNote  Exons 20 and 21, which contain the RNaseII domain, were flanked with loxP sites. A neo with a 5' loxP site was included in the targeting vector and was inserted into intron 19.
  • mutations:
  • Insertion
  • synonyms:
  • dicer<lox>,
  • Dicer<flox>,
  • dicer<lox>,
  • Dicer<flox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

53 Publication categories